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1

Current Approaches to Germline Cancer Genetic Testing

Stoffel, Elena M., Carethers, John M.

Journal:

Annual Review of Medicine

Year:

2020

Language:

english

File:

PDF, 276 KB

english, 2020

2

Bone morphogenetic protein and activin signaling in colorectal cancer

Barbara H. Jung, Stayce E. Beck, John M. Carethers

Journal:

Current Colorectal Cancer Reports

Year:

2008

Language:

english

File:

PDF, 261 KB

english, 2008

3

Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

Carethers, John M., Braun, Jonathan, Sands, Bruce E.

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 287 KB

english, 2015

4

Cancer health disparities in racial/ethnic minorities in the United States

Zavala, Valentina A., Bracci, Paige M., Carethers, John M., Carvajal-Carmona, Luis, Coggins, Nicole B., Cruz-Correa, Marcia R., Davis, Melissa, de Smith, Adam J., Dutil, Julie, Figueiredo, Jane C., Fo

Journal:

British Journal of Cancer

Year:

2020

File:

PDF, 819 KB

2020

5

Disparities in Cancer Prevention in the COVID-19 Era

Carethers, John M., Sengupta, Rajarshi, Blakey, Rea, Ribas, Antoni, D'Souza, Gypsyamber

Journal:

Cancer Prevention Research

Year:

2020

File:

PDF, 1.54 MB

2020

6

Evidence for an hMSH3 defect in familial hamartomatous polyps

Sherry C. Huang, Jeffrey K. Lee, E. Julieta Smith, Ryan T. Doctolero, Akihiro Tajima, Stayce E. Beck, Noel Weidner, John M. Carethers

Journal:

Year:

2011

Language:

english

File:

PDF, 349 KB

english, 2011

7

John Cunningham virus T-antigen expression in anal carcinoma

Sonia Ramamoorthy, Bikash Devaraj, Katsumi Miyai, Linda Luo, Yu-Tsueng Liu, C. Richard Boland, Ajay Goel, John M. Carethers

Journal:

Year:

2011

Language:

english

File:

PDF, 263 KB

english, 2011

8

Clinicopathological features and microsatellite instability (MSI) in colorectal cancers from African Americans

Hassan Ashktorab, Duane T. Smoot, Haleh Farzanmehr, Marie Fidelia-Lambert, Bahram Momen, Linda Hylind, Christine Iacosozio-Dononue, John M. Carethers, Ajay Goel, C. Richard Boland, Francis M. Giardiel

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 273 KB

english, 2005

9

Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers

Barbara Jung, E. Julieta Smith, Ryan T. Doctolero, Pascal Gervaz, Julio C. Alonso, Katsumi Miyai, Temitope Keku, Robert S. Sandler, John M. Carethers

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

10

Clinical and experimental observations on frostbite

John P Heggers, Martin C Robson, K Manavalan, Mark D Weingarten, John M Carethers, Jane A Boertman, Robert J Sachs

Journal:

Annals of Emergency Medicine

Year:

1987

Language:

english

File:

PDF, 307 KB

english, 1987

11

Experimental and clinical observations on frostbite

John P Heggers, Martin C Robson, K Manavalen, Mark D Weingarten, John M Carethers, Jane A Boertman, David J Smith Jr, Robert J Sachs

Journal:

Annals of Emergency Medicine

Year:

1987

Language:

english

File:

PDF, 595 KB

english, 1987

12

Quality of life and diet intervention in individuals at risk for recurrence of colorectal adenomas

Bilge Pakiz, Shirley W. Flatt, Kathleen C. Mills, Lindsay J. Jordan, John M. Carethers, Cheryl L. Rock

Journal:

Psycho-Oncology

Year:

2005

Language:

english

File:

PDF, 105 KB

english, 2005

13

Loss of heterozygosity and HIV infection in patients with anal squamous-cell carcinoma

Pascal Gervaz, Jonathan Efron, Alfredo A. Poza, Sung W. Chun, Thu-Thao T. Pham, Sherry Woodhouse, Steven D. Wexner, John M. Carethers

Journal:

Diseases of the Colon & Rectum

Year:

2001

Language:

english

File:

PDF, 704 KB

english, 2001

14

The inflammatory response in transgastric surgery: gastric content leak leads to localized inflammatory response and higher adhesive disease

Sonia L. Ramamoorthy, Jeffrey K. Lee, Linda Luo, Yoav Mintz, John Cullen, David W. Easter, Michelle K. Savu, Alana Chock, John Carethers, Santiago Horgan, Mark A. Talamini

Journal:

Surgical Endoscopy

Year:

2010

Language:

english

File:

PDF, 203 KB

english, 2010

15

Microsatellite Instability, EMAST, and Morphology Associations with T Cell Infiltration in Colorectal Neoplasia

Sun-Young Lee, Katsuya Miyai, Hye Seung Han, Dae-Yong Hwang, Moo Kyung Seong, Heekyung Chung, Barbara H. Jung, Bikash Devaraj, Kathleen L. McGuire, John M. Carethers

Journal:

Digestive Diseases and Sciences

Year:

2012

Language:

english

File:

PDF, 330 KB

english, 2012

16

The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch Syndrome: from bench to bedside

C. Richard Boland, Minoru Koi, Dong K. Chang, John M. Carethers

Journal:

Familial Cancer

Year:

2008

Language:

english

File:

PDF, 525 KB

english, 2008

17

Relationship of EMAST and Microsatellite Instability Among Patients with Rectal Cancer

Bikash Devaraj, Aaron Lee, Betty L. Cabrera, Katsumi Miyai, Linda Luo, Sonia Ramamoorthy, Temitope Keku, Robert S. Sandler, Kathleen L. McGuire, John M. Carethers

Journal:

Journal of Gastrointestinal Surgery

Year:

2010

Language:

english

File:

PDF, 436 KB

english, 2010

18

Secondary Prevention of Colorectal Cancer: Is There an Optimal Follow-up for Patients with Colorectal Cancer?

John M. Carethers

Journal:

Current Colorectal Cancer Reports

Year:

2010

Language:

english

File:

PDF, 132 KB

english, 2010

19

Tobacco smoking and risk of recurrence for squamous cell cancer of the anus

Sonia Ramamoorthy, Linda Luo, Elizabeth Luo, John M. Carethers

Journal:

Cancer Detection and Prevention

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

20

BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK

Stayce E. Beck, Barbara H. Jung, Eunice Del Rosario, Jessica Gomez, John M. Carethers

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 705 KB

english, 2007

21

Flanking nucleotide specificity for DNA mismatch repair-deficient frameshifts within Activin Receptor 2 (ACVR2)

Heekyung Chung, Joy Chaudhry, Jenny F. Lai, Dennis J. Young, John M. Carethers

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2012

Language:

english

File:

PDF, 936 KB

english, 2012

22

Effect of H2O2 on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines

Dong Kyung Chang, Ajay Goel, Luigi Ricciardiello, Dong Ho Lee, Christina L. Chang, John M. Carethers, C.Richard Boland

Journal:

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

23

Germline characterization of early-aged onset of hereditary non-polyposis colorectal cancer

Sherry C. Huang, Joel E. Lavine, Patricia S. Boland, Robert O. Newbury, Richard Kolodner, Thu-Thao T. Pham, Christian N. Arnold, C.Richard Boland, John M. Carethers

Journal:

The Journal of Pediatrics

Year:

2001

Language:

english

File:

PDF, 308 KB

english, 2001

24

Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer

Pascal Gervaz, Jean-Philippe Cerottini, Hanifa Bouzourene, Dieter Hahnloser, Christy L Doan, Jean Benhattar, Pascal Chaubert, Michelle Secic, Michel Gillet, John M Carethers

Journal:

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

25

Prognostic significance of allelic loss at chromosome 18q21 for stage II colorectal cancer

John M. Carethers, Mary T. Hawn, Joel K. Greenson, Charles L. Hitchcock, C.Richard Boland

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 117 KB

english, 1998

26

Mismatch repair proficiency and in vitro response to 5-fluorouracil

John M. Carethers*, ‡, Dharam P. Chauhan*, Daniel Fink*, Sibylle Nebel*, Robert S. Bresalier§, Stephen B. Howell*, ‡, C.Richard Boland*, ‡, ∥

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 138 KB

english, 1999

27

Proteomics, Genomics, and Molecular Biology in the Personalized Treatment of Colorectal Cancer

John M. Carethers

Journal:

Journal of Gastrointestinal Surgery

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

28

In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer

Michael C. Luce, Giancarlo Marra, Dharam P. Chauhan, Luigi Laghi, John M. Carethers, Sajeev P. Cherian, Mary Hawn, Cameron G. Binnie, Lauren N.W. Kam-Morgan, Matthew C. Cayouette, Minoru Koi, C.Richar

Journal:

Gastroenterology

Year:

1995

Language:

english

File:

PDF, 2.86 MB

english, 1995

29

How Accurately Do Patients Report Their Colonoscopy Results?

Lisa Madlensky, Barbara H. Jung, Gerald L. Tolbert, Sepideh Safari, John M. Carethers

Journal:

Gastrointestinal Endoscopy

Year:

2008

Language:

english

File:

PDF, 48 KB

english, 2008

30

Aphthous colitis in a young patient with diverticulitis

Barbara H Jung, John Carethers, John J Garvie

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 51 KB

english, 2002

31

Colorectal cancer prevention and treatment

C.Richard Boland, Frank A. Sinicrope, Dean E. Brenner, John M. Carethers

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 192 KB

english, 2000

32

True association of germline PTEN mutation with juvenile polyposis syndrome

Sherry C. Huang, Christine R. Chen, Thu-Thao T. Pham, Joel E. Lavine, Sharon F. Taylor, Robert O. Newbury, John M. Carethers

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 234 KB

english, 2000

33

Dinucleotide, but not mononucleotide microsatellite instability, is present in familial juvenile polyps

John M. Carethers, Ryan T. Doctolero, Betty M. Lopez, Julio C. Alonso, Sherry C. Huang, Thu-Thao T. Pham

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 186 KB

english, 2000

34

Germline characterization of early-aged onset of HNPCC

Sherry C. Huang, Joel E. Lavine, Patricia S. Boland, Richard Kolodner, Robert O. Newbury, C. Richard Boland, John M. Carethers

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 167 KB

english, 2000

35

The mismatch repair (MMR) complex hMutSα recognizes 5-fluorouracil (5FU) modified DNA: a mechanism for 5FU sensitivity

Akihiro Tajima, Betty L. Cabrera, Heather McMahon, Ryan Doctolero, Sherry Huang, John Carethers

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

36

The mismatch repair (MMR) protein hMSH3 is lost from polyp epithelium of patients with PTEN germline hamartomatous syndromes

Sherry C. Huang, Arun Swaminath, E. Julieta Smith, Ryan T. Doctolero, Anna Dreilinger, John M. Carethers

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

37

Influence of race on the prevalence of microsatellite unstable (MSI) colorectal cancers

Ryan T. Doctolero, Temitope Keku, Akihiro Tajima, Chris Martin, Katsumi Miyai, Robert S. Sandler, John M. Carethers

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

38

188 Activin Signaling in Microsatellite Stable (MSS) Colon Cancers Is Disrupted By a Combination of Genetic and Epigenetic Mechanisms

Barbara H. Jung, Jessica Gomez, Eddy Chau, Jennifer Cabral, Deena Ream-Robinson, Sung Kwan Shin, Ajay Goel, John M. Carethers

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

39

40 Dichotomous Signaling Mechanisms for Activin-Induced Growth Suppression and Migration in Colon Cancer Cells

Barbara H. Jung, Jennifer Cabral, Jessica Gomez, Stayce E. Beck, John M. Carethers

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

40

801 Determination of Mutation Frequency and Rate of Activin Receptor 2 (Acvr2) and Transforming Growth Factor Receptor 2 (Tgfbr2) in Colorectal Cells with Different DNA Mismatch Repair (MMR) Defects

Heekyung Chung, Dennis J. Young, Thuy-Anh T. Le, Jeffrey K. Lee, Deena Ream-Robinson, John M. Carethers

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 78 KB

english, 2008

41

Target gene mulations are not predictors of survival in stage II high-frequency microsatellite unstable (MSI-H) colorectal cancer

John M. Carethers, E. Julieta Smith, Ajay Goel, Christian N. Arnold, Christy L. Doan, Julio C. Alonso, Pascal Gervaz, Jean-Philippe Cerottini, Hanifa Bouzourene, Linda Wasserman, Joel K. Greenson, C R

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

42

Chromosomal vs microsatellite instability in colorectal cancers: Evidence for previously unrecognized pathways

Ajay Goel, Christian N. Arnold, Dong Kyung Chang, Luigi Ricciardiello, Dharam P. Chauhan, John M. Carethers, Linda Wasserman, Carolyn Compton, Donna Niedzwiecki, Robert J. Mayer, Monica M. Bertagnolli

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 325 KB

english, 2001

43

Hyperpield cancer cells are more resistant to oxyradical stress

Dong Kyung Chang, Ajay Goel, Luigi Ricciardiello, Se-Hyun Cho, John M. Carethers, C. Richard Boland

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

44

JC virus is integrated in the SW488 colon cancer cell line and express a trancated T antigen: A mechanism to generate and carry chromosomal instability

Luigi Ricciardiello, Ajay Goel, Dong Kyung Chang, Antonio Fiorino, John M. Carethers, Luigi Laghi, C. Richard Boland

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 176 KB

english, 2001

45

164 NF-κB Mediates TGFβ-Induced PTEN Suppression in Human Pancreatic Cancer Cells via SMAD-Independent Signaling

Jimmy Chow, Makiko Ban, Helen L. Wu, Heekyung Chung, John M. Carethers

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

46

350 Cyclin E and Histone H3 Levels Are Regulated By 5-Fluorouracil (5-FU) in a DNA Mismatch Repair (MMR)-Dependent Manner

Heekyung Chung, John M. Carethers

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

47

841 Mechanism for Selectivity of Specific Exonic Activin Receptor 2 (ACVR2) Frameshift Mutation in Colorectal Cells with Defective DNA Mismatch Repair (MMR)

Heekyung Chung, Claudia G. Lopez, Dennis J. Young, Betty L. Cabrera, Deena Ream-Robinson, John M. Carethers

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 78 KB

english, 2009

48

224 Specific Nucleotides That Flank Coding Microsatellites of Activin Receptor 2 (ACVR2) Determine Exonic Selectivity and Control Frameshift Mutation Rates in Defective DNA Mismatch Repair (MMR)

Heekyung Chung, Jenny Lai, Joy Holmstrom, Dennis J. Young, John M. Carethers

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 93 KB

english, 2010

49

221 TGFβ Destabilizes PTEN via Dephosphorylation to Promote Pancreatic Cancer Cell Motility

Jimmy Y. Chow, Flang Nguyen, Mei Huang, John M. Carethers

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 51 KB

english, 2010

50

EMAST Mutation in Colorectal Cancer Cells is Experimentally Associated With hMSH3−/− and Nearly Mimics Complete DNA Mismatch Repair Loss

Heekyung Chung, Stephanie Tseng-Rogenski, Joy Chaudhry, Dennis J. Young, John M. Carethers

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 121 KB

english, 2011

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